Anticancer Products

Approx. Rs 6,500 / BottleGet Latest Price

Resof L (Ledipasvir Sofosbuvir)

Brand name: Resof L

Active Ingeridents(Generic Name) : Ledipasvir Sofosbuvir

Company Name: Dr.Reddy’s

Package: 28 tablets/bottle

Strength : Ledipasvir 90mg Sofosbuvir 400mg

Indication:

Treating chronic hepatitis C virus (HCV) infection in certain patients.

Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir and Ledipasvir is a combination and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.

Mechanism of action:

Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.

Dosage and Administration:

Ledipasvir-sofosbuvir (90 mg/400 mg) is a fixed-dose combination tablet . The recommended dosage is one tablet once daily, with or without food.

Side effects:

The following are the Common side effects

· fatigue

• nausea
• headache
• diarrhea

· insomnia

Precaution:

· Tell your doctor or dentist that you take ledipasvir and sofosbuvir before you receive any medical or dental care, emergency care, or surgery.

· Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HCV to others.

Store: ledipasvir Sofosbuvir  room temperature away from moisture and heat 

Additional Information:

Approx. Rs 14,220 / UnitGet Latest Price

Approx. Rs 6,836 / VialGet Latest Price

Cytogem Uses:

Cytogem Injection is used for Treatment of ovarian cancer, Treatment of breast cancer, Treatment of non-small cell lung cancer, Treatment of pancreatic cancer and other conditions. Cytogem Injection may also be used for purposes not listed in this medication guide.

Cytogem Injection contains Gemcitabine as an active ingredient.

Cytogem Injection works by killing cells undergoing DNA synthesis and blocks the progression of cells through the G1/S phase boundary.

Dr Reddys Labs manufactures Cytogem Injection.

Cytogem Injection - Precautions & How to Use

Before using Cytogem Injection, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition.  Tell your doctor if your condition persists or worsens.

Approx. Rs 396 / StripGet Latest Price

Brand Name ??Lanolimus 0.25mg

Generic Name ??Everolimus

Company Mylan

Strength0.25mg

Packing ??1x10 Tablets

Indication

Everolimus is used to treat various types of cancer (such as kidney, breast, pancreas, lung, stomach/intestinal cancers). Everolimus is also used in people with a certain genetic disorder (tuberous sclerosis complex) to treat certain types of benign tumors in the brain or kidney. It works by slowing or stopping the growth of cancer or tumor cells.

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How to use Everolimus

Take this medication by mouth as directed by your doctor, usually once daily. You may take this medication with or without food, but it is important to choose one way and take this medication the same way with every dose. Swallow this medication whole with a glass of water. Do not crush or chew the tablets.

Read the Patient Information Leaflet if available from your pharmacist before you start taking everolimus and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Do not change dosage forms of this medication without checking with your doctor or pharmacist.

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Side Effects

Diarrhea, nausea/vomiting, decreased appetite, weight loss, changes in taste, nosebleeds, dry skin, dizziness, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

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Precautions

Before taking everolimus, tell your doctor or pharmacist if you are allergic to it; or to sirolimus or temsirolimus; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Approx. Rs 12,990 / StripGet Latest Price

Approx. Rs 390 / PackGet Latest Price

Brand name: Daunotec

Active Ingeridents (Generic Name) : Daunorubicin

Company Name: Cipla

Package: Vial

Strength : 20mg

Indication:It is used in the treatment of Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL). It may be used in combination with other medicines. It may also be used for other conditions as determined by your doctor.

Mechanism of action:

Daunotec (Daunorubicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunotec (Daunorubicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Dosage & Administration:

• Daunotec (Daunorubicin) is given by intravenous injection (IV). The syringe needle is placed directly into the tubing of a freely flowing IV solution into a vein or central line and the drug is given over several minutes.
• Daunotec (Daunorubicin) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. The nurse or doctor who gives this drug must be carefully trained. If you notice redness or swelling at the IV site while you are receiving Daunotec (Daunorubicin) , alert your health care professional immediately.
• The amount of Daunotec (Daunorubicin) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dose and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; hair loss; loss of appetite; mouth pain; nausea; sore throat; stomach pain; tiredness; weakness.

Precaution:

• Before starting Daunotec (Daunorubicin) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , products containing unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Daunotec (Daunorubicin) .
• You may be more sensitive to sunlight, take extra care to avoid sun exposure.
• People with congestive heart failure, those who have already had high doses of this drug or a similar drug, and those with permanent problems with blood counts (bone marrow suppression) cannot receive this drug.

Store: Daunotec (Daunorubicin) is usually handled and stored by a health care provider. If you are using Daunotec (Daunorubicin) at home, store Daunotec (Daunorubicin) as directed by your pharmacist or health care provider. Keep Daunotec (Daunorubicin) out of the reach of children and away from pets.

Approx. Rs 16,871 / BottleGet Latest Price

Temonat (Temozolomide) 

Brand name: Temonat

Active Ingeridents(Generic Name) : Temozolomide 

Company Name: Natco

Package: 5 Capsules

Strength: 250mg

Indication:

It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.

Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

Mechanism of action:

The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O⁶-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide) . 

Dosage and Administration:

• This medication is given in a capsule form by mouth.
• Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
• Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
• The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.

Precaution:

• Before starting Temonat (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor''s approval while taking Temonat (Temozolomide) .
• Let your health care provider know if you''ve had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

Store: Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.

Approx. Rs 850 / StripGet Latest Price

Introduction:

Veenat 400mg Tablet consists of the active ingredient Imatinib. Veenat 400mg Tablet is used to treat blood cancer (Chronic Myeloid leukaemia, acute lymphocytic leukaemia) and gastrointestinal stromal tumour even if it is considered not curative.

Chronic Myelogenous Leukemia (CML) is a type of blood cancer characterized by uncontrolled production of stem cells in the bone marrow and an increased number of mature granulocytes in the blood. This treatment aims to prolong survival, prevent the disease from worsening, and ultimately reduce the signs and symptoms.

Uses of Veenat 400mg Tablet:

Veenat 400mg Tablet is either used alone or in combination with other chemotherapy treatments to treat the following conditions:

• Chronic eosinophilic leukaemia
• Chronic myeloid leukaemia
• Gastrointestinal stromal tumour (Stomach cancer)
• Dermatofibrosarcoma protuberans (skin cancer).

How Veenat 400mg Tablet Works: 

BCR-ABL tyrosine kinase enzyme is responsible for the uncontrolled division of cells in blood cancer. Veenat 400mg disrupts the signalling route of protein kinase enzyme. It targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store in a place protected from moisture, in a temperature not exceeding 30¿¿C.

How to use Veenat 400mg Tablet: 

Do not crush the tablets. Avoid direct contact of crushed tablets with the skin or mucous membranes. Use as directed by your oncologist.

Safety Advice:

Pregnancy: 

This medicine is not intended for use during pregnancy. Talk to your physician if you are pregnant or think you could be pregnant.

Breastfeeding: 

Consult your physician for advice on taking this medicine if you are a breastfeeding mother.

Liver:

Inform your physician before starting this treatment if you have liver disease. Ensure that your physician monitors your liver functions every month.

Kidney:

Inform your physician before starting this treatment if you have kidney disease. Make sure that your physician monitors your kidney functions regularly.

Driving: 

Exercise caution while driving and using machines during this treatment.

Others:

• Inform your physician before taking this medicine if you have lung problems, breathing trouble, heart problems, or other health issues.
• Inform your physician if you are hypersensitive to Imatinib or its ingredients.

• Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

   

  Serious:

  • Hemolytic Anaemia
  • Low levels of WBC and platelets in the blood
  • Heart failure and swelling
  • Tiredness
  • Fever
  • Bleeding
  • Liver abnormalities
  • Kidney disorders
  • Growth retardation in children

   

  Common:

  • Nausea, vomiting, diarrhoea
  • Rashes
  • Sensitivity to light
  • Stomach pain
  • Muscle cramps

Additional Information:

Approx. Rs 1,400 / VialGet Latest Price

Bandrone (Ibandronic acid) 

Brand name: Bandrone 6mg injection

Active Ingeridents (Generic Name) : Ibandronic acid

Company Name: Natco

Package: Vial

Strength : 6mg

Indication:

It is used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels).

Also, Treating osteoporosis (weak bones) in women who are past menopause. It may also be used for other conditions as determined by your doctor. Ibandronate is a bisphosphonate. It works by slowing bone loss and allowing new bone to be formed.

Mechanism of action:

The action of Bandrone (Ibandronic acid)on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting farnesyl pyrophosphate (FPP) synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Dosage & Administration:

Use Bandrone (Ibandronic acid)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Bandrone (Ibandronic acid)comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Bandrone (Ibandronic acid)refilled.

· Bandrone (Ibandronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.

· Ask your health care provider any questions you may have about how to use Bandrone (Ibandronic acid).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; heartburn; mild arm, back, leg, muscle, or joint pain; mild flu-like symptoms (eg, mild fever, chills, tiredness, weakness, joint or muscle aches); nausea; pain, swelling, or redness at the injection site; stomach pain or upset.

Precaution:

Before taking Bandrone (Ibandronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates; or if you have any other allergies.

Store: Bandrone (Ibandronic acid)is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

Additional Information:

Approx. Rs 950 / PieceGet Latest Price

Brand Name: Zoldria

Generic Name: Zoledronic Acid

Company Name: CIPLA

Strength: Zoledronic Acid 4mg

Packing: Vial

Zoldria Injection is used for Bone metastases, Osteoporosis, Hypercalcemia, Multiple myeloma, Paget's disease and other conditions. Zoldria Injection may also be used for purposes not listed in this medication guide.

Zoldria Injection contains Zoledronate as an active ingredient.

Zoldria Injection works by lowering high blood calcium levels.

Cipla manufactures Zoldria Injection.

Additional Information:

Approx. Rs 850 / VialGet Latest Price

Approx. Rs 755 / StripGet Latest Price

Approx. Rs 2,450 / PackGet Latest Price

Bonimet (Ibandronic acid) 

Brand name: Bonimet

Active Ingeridents (Generic Name) : Ibandronic acid

Company Name: Intas

Package: Vial

Strength : 6mg

Indication:

It is used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels).

Also, Treating osteoporosis (weak bones) in women who are past menopause. It may also be used for other conditions as determined by your doctor. Ibandronate is a bisphosphonate. It works by slowing bone loss and allowing new bone to be formed.

Mechanism of action:

The action of Bonimet (Ibandronic acid)on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting farnesyl pyrophosphate (FPP) synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Dosage & Administration:

Use Bonimet (Ibandronic acid)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Bonimet (Ibandronic acid)comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Bonimet (Ibandronic acid)refilled.

· Bonimet (Ibandronic acid) is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.

· If you miss your scheduled dose of Bonimet (Ibandronic acid), contact your doctor to reschedule it as soon as possible. Do not receive your injection more often than once every 3 months.

Ask your health care provider any questions you may have about how to use Bonimet (Ibandronic acid).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; heartburn; mild arm, back, leg, muscle, or joint pain; mild flu-like symptoms (eg, mild fever, chills, tiredness, weakness, joint or muscle aches); nausea; pain, swelling, or redness at the injection site; stomach pain or upset.

Precaution:

Before taking Bonimet (Ibandronic acid), tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates; or if you have any other allergies.

Store: Bonimet (Ibandronic acid)is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets..

Approx. Rs 25,500 / PackGet Latest Price

Faslodex (Fulvestrant)

Brand name: Faslodex

Active Ingeridents (Generic Name) :Fulvestrant)

Company Name: Astrazeneca

Package: One prefilled syringe containing 5ml or 250mg Faslodex (Fulvestrant)

Strength : 250mg/5ml

Indication:

Faslodex (Fulvestrant) is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body.

Faslodex (Fulvestrant) is used to treat a certain type of hormone-related breast cancer in postmenopausal women, when the cancer has spread to other parts of the body after treatment with anti-estrogen medication.

Faslodex (Fulvestrant) is also used together with a medicine called palbociclib, to treat certain hormone-related breast cancer that has progressed or spread after treatment with hormonal therapy.

Mechanism of action:

Faslodex (Fulvestrant) competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. First, Faslodex (Fulvestrant) binds to the receptors and downregulates them so that estrogen is no longer able to bind to these receptors. Second, Faslodex (Fulvestrant) degrades the estrogen receptors to which it is bound. Both of these mechanisms inhibit the growth of tamoxifen-resistant as well as estrogen-sensitive human breast cancer cell lines. 

Dosage & Administration:

As an injection into the muscle (intramuscular, IM), Faslodex (Fulvestrant) is usually given as a once a month injection. Your doctor will determine any variations to this dosing or schedule.

Side effects:

Get emergency medical help if you have signs of an allergic reaction to Faslodex (Fulvestrant): hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Faslodex (Fulvestrant) side effects may include:

Headache, bone pain, joint pain, muscle pain, nausea, vomiting, loss of appetite, constipation; weakness, feeling tired; cough, trouble breathing; abnormal liver function tests; hot flashes; or pain where the medicine was injected.

Precaution:

• Before starting Faslodex (Fulvestrant) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing unless your doctor specifically permits this.
• Let your health care professional know if you have ever had a blood clot that required medical treatment.
• Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (Faslodex (Fulvestrant) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

Store: Faslodex (Fulvestrant) is handled and stored by a health care provider. Keep all medicines out of the reach of children and away from pets.

Approx. Rs 370 / PIECEGet Latest Price

Daunorubitec (Daunorubicin)

Brand name: Daunorubitec

Active Ingeridents (Generic Name) : Daunorubicin

Company Name: United Biotech

Package: Vial

Strength : 20mg

Indication:

It is used in the treatment of Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL). It may be used in combination with other medicines. It may also be used for other conditions as determined by your doctor.

Mechanism of action:

Daunorubitec (Daunorubicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubitec (Daunorubicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Dosage & Administration:

• Daunorubitec (Daunorubicin) is given by intravenous injection (IV). The syringe needle is placed directly into the tubing of a freely flowing IV solution into a vein or central line and the drug is given over several minutes.
• Daunorubitec (Daunorubicin) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein. The nurse or doctor who gives this drug must be carefully trained. If you notice redness or swelling at the IV site while you are receiving Daunorubitec (Daunorubicin) , alert your health care professional immediately.
• The amount of Daunorubitec (Daunorubicin) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dose and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; hair loss; loss of appetite; mouth pain; nausea; sore throat; stomach pain; tiredness; weakness.

Precaution:

• Before starting Daunorubitec (Daunorubicin) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , products containing unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Daunorubitec (Daunorubicin) .
• You may be more sensitive to sunlight, take extra care to avoid sun exposure.
• People with congestive heart failure, those who have already had high doses of this drug or a similar drug, and those with permanent problems with blood counts (bone marrow suppression) cannot receive this drug.

Store: Daunorubitec (Daunorubicin) is usually handled and stored by a health care provider. If you are using Daunorubitec (Daunorubicin) at home, store Daunorubitec (Daunorubicin) as directed by your pharmacist or health care provider. Keep Daunorubitec (Daunorubicin) out of the reach of children and away from pets.

Approx. Rs 18,000 / PackGet Latest Price

Fulvenat (Fulvestrant)

Brand name: Fulvenat 

Active Ingeridents (Generic Name) : Fulvestrant

Company Name: Natco 

Package: One prefilled syringe containing 5ml or 250mg Fulvenat (Fulvestrant)

Strength : 250mg/5ml

Indication:

Fulvenat (Fulvestrant) is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body.

Fulvenat (Fulvestrant) is used to treat a certain type of hormone-related breast cancer in postmenopausal women, when the cancer has spread to other parts of the body after treatment with anti-estrogen medication.

Fulvenat (Fulvestrant) is also used together with a medicine called palbociclib, to treat certain hormone-related breast cancer that has progressed or spread after treatment with hormonal therapy.

Mechanism of action:

Fulvenat (Fulvestrant) competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. First, Fulvenat (Fulvestrant) binds to the receptors and downregulates them so that estrogen is no longer able to bind to these receptors. Second, Fulvenat (Fulvestrant) degrades the estrogen receptors to which it is bound. Both of these mechanisms inhibit the growth of tamoxifen-resistant as well as estrogen-sensitive human breast cancer cell lines. 

Dosage & Administration:

As an injection into the muscle (intramuscular, IM), Fulvenat (Fulvestrant) is usually given as a once a month injection. Your doctor will determine any variations to this dosing or schedule.

Side effects:

Get emergency medical help if you have signs of an allergic reaction to Fulvenat (Fulvestrant): hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Fulvenat (Fulvestrant) side effects may include:

Headache, bone pain, joint pain, muscle pain, nausea, vomiting, loss of appetite, constipation; weakness, feeling tired; cough, trouble breathing; abnormal liver function tests; hot flashes; or pain where the medicine was injected.

Precaution:

• Before starting Fulvenat (Fulvestrant) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing unless your doctor specifically permits this.
• Let your health care professional know if you have ever had a blood clot that required medical treatment.
• Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (Fulvenat (Fulvestrant) may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).

Store: Fulvenat (Fulvestrant) is handled and stored by a health care provider. Keep all medicines out of the reach of children and away from pets.