Hepatitis Medicine

Approx. Rs 2,500 / BottleGet Latest Price

X-Vir (Entecavir) is used as an antiviral treatment for patients suffering from a chronic hepatitis B infection. It is classified as a nucleoside analog, and it works by stopping the spread of the virus. Because it can inhibit an enzyme called viral DNA polymerase, it is able to prevent the spread and proliferation of the virus. This can help to reduce the overall amount of the virus present in the body, while also helping to lessen damage to the liver.

X-Vir (Entecavir) is administered orally. It comes as either 0.5mg or 1mg strength tablets. Your physician will be responsible for deciding the right dosage. Adults treating hepatitis B who are deemed to be nucleoside therapy naive may be directed to take 0.5mg once per day. However, some patients may be directed to take 1mg per day (usually in cases of mutations of the virus that are resistance to lamivudine or otherwise difficult to treat). Patients must strictly comply with the instructions given by their physician.

The use of X-Vir (Entecavir) could cause side effects. Tell the physician providing medical care if this happens. Some possible examples are given here:

• Diarrhea
• Headaches
• Digestive discomfort
• Sleepy or fatigued feeling
• Nausea, possibly resulting in vomiting

Although the majority of side effects caused by this medicine are less serious in nature, there is a possibility that some patients will be affected by reactions which are significantly more serious. You must attend the hospital or see your physician straight away if you are affected by coldness, persistent vomiting, feeling weak or any other serious side effects not mentioned here.

Serious conditions including hepatomegaly and lactic acidosis are known to have occurred in some patients treated with X-Vir (Entecavir) for their condition. Discuss this with your physician before starting therapy.

This medication will not cure the infection, and you will need continuous medical treatment in order to manage your condition.

Approx. Rs 6,999 / BottleGet Latest Price

Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.

Daclahep:

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Additional Information:

Approx. Rs 8,500 / BottleGet Latest Price

Uses of Velpaclear Tablet

Velpaclear Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.

How Velpaclear Tablet works

Velpaclear Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

How to use Velpaclear Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Velpaclear Tablet may be taken with or without food, but it is better to take it at a fixed time.

Approx. Rs 6,500 / BottleGet Latest Price

Sovihep 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.

Dacihep:

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Additional Information:

Approx. Rs 10,500 / BottleGet Latest Price

We are offering Velpanat Tablet.

Specifications:

Brand name: Velpanat

Active Ingredients: Velpatasvir & Sofosbuvir

Company Name: Natco

Package:28 tablets/bottle

Strength: Velpatasvir 100Mg Sofosbuvir 400Mg

Velpanat is the combination of Sofosbuvir 400mg & Velpatasvir 100mg.Velpanat launched by Natco.Velpanat is a Pangenotype Hepatitis C drug.Velpanat is generic version of Eculpsa.Velpanat can be used from 12 weeks to 24weeks depend upon the viral load.

Approx. Rs 8,500 / BottleGet Latest Price

Indication:

Resof Total is an combination of velpatasvir 100mg+ Sofosbuvir 400mg. Resof Total is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing the viral NS5A inhibitor velpatasvir and sofosbuvir,a nucleotide inhibitor of the viral RNA polymerase. It is the first treatment, that works for all genotypic, and is taken entirely by mouth. A single tablet regimen is used for adults with genotype 1-6 chronic hepatitis C virus (HCV) infection with pangenotypic activity.

This medication is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. sofosbuvir velpatasvir, sofosbuvir and velpatasvir, velpatasvir sofosbuvir, sofosbuvir velpatasvir brand name, It may sometimes be used with another antiviral medication (ribavirin). These drugs velpatasvir genotype 3 work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir velpatasvir cost, epclusa sofosbuvir velpatasvir, sofosbuvir plus velpatasvir available velpatasvir india.

Dosage and Administration:

Take Resof Total exactly as your healthcare provider tells you to.

• Patients without cirrhosis or with compensated cirrhosis (Child-Pugh A): Resof Total for 12 weeks.
• Patients with decompensated cirrhosis (Child-Pugh B or C): Resof Total.
• plus weight-based ribavirin with food for 12 weeks
• Weight-based ribavirin dose.
• Less than 75 kg: 1000 mg/day PO divided BID
• ≥75 kg: 1200 mg/day PO divided BID
• Ribavirin starting dose and on-treatment dosage should be modified based on hemoglobin and creatinine clearance
• Dose modification:Severe renal impairment (eGFR less than 30mL/min/1.73 m²) or ESRD: No dosage recommendation can be give owing to higher exposures (up to 20-fold) of the predominant sofosbuvir metabolite

Additional Information:

Approx. Rs 4,500 / BottleGet Latest Price

Indication:

It is used for the treatment of hepatitis Cvirus (HCV) infection. It has been marketed since 2013. Compared to previous treatments, Sofosbuvir-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy. Sofovir (Sofosbuvir) allows most patients to be treated successfully without the use of peginterferon, an injectable drug with severe side effects. that is a key component of older drug combinations for the treatment of HCV. Sofovir (Sofosbuvir)is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone. It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection. Sofovir (Sofosbuvir) is also used in HCV patients with an HIV coinfection. The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of Sofosbuvir plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.

Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.

The recommended daily dose of is 400mg tablet to be taken once daily with or without food. Sofovir (Sofosbuvir) should be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults.It is highly advisable to administer the drug under strict medical supervision and advice.

Approx. Rs 4,000 / BottleGet Latest Price

Indication:

It is used for the treatment of hepatitis Cvirus (HCV) infection. It has been marketed since 2013. Compared to previous treatments, sofosbuvir-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy. Sofosbuvir allows most patients to be treated successfully without the use of peginterferon,an injectable drug with severe side effects^. that is a key component of older drug combinations for the treatment of HCV.

Sofosbuvir is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone. It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection. Sofosbuvir is also used in HCV patients with an HIV coinfection. The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of sofosbuvir plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.

Sofosbuvir 400mg tablets  is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online. 

Dosage and Administration:

The recommended daily dose of Sofosbuvir is 400mg tablet to be taken once daily with or without food. Sofosbuvir should be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults. It is highly advisable to administer the drug under strict medical supervision and advice.

Approx. Rs 2,097 / BottleGet Latest Price

X-vir (Entecavir)

• Brand name: X-vir 
• Active Ingeridents(Generic Name) : Entecavir 
• Company Name: Natco
• Package: 30 Tablets
• Strength : 0.5mg

Indication: Entecavir is used to treat long-term hepatitis B infection. Hepatitis B is an infection of the liver caused by the hepatitis B virus. Long-term infection can cause liver damage, rarely liver cancer, and liver failure. Entecavir helps to decrease the amount of hepatitisB virus in your body. It is unknown if this medication lowers your chance of gettingliver cancer or liver damage. Entecavir is an antiviral that belongs to a class of drugs known as hepatitis B virus nucleoside reverse transcriptase inhibitors.

Mechanism of action:

Entecavir is mainly used to treat chronic hepatitis B infection in adults and children 2 years and older with active viral replication and evidence of active disease.It is also used to prevent HBV reinfection after liver transplant and to treat HIV patients infected with HBV. Entecavir is weakly active against HIV, however it is not recommended for use in HIV-HBV co-infected patients without a fully suppressive anti-HIV regimen as it may select for resistance to lamivudine and emtricitabine in HIV. 

Dosage and Administration:

· Take entecavir on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal.

· Entecavir works best if it is taken at the same time each day.

· Continue to take entecavir even if you feel well. Do not miss any doses.

· If you miss a dose of entecavir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

Dizziness; headache; nausea; tiredness. 

Precaution:

An overdose entecavir Unlikely to threaten life, call an emergency room or a poison control center for advice if you suspect that a very large dose of entecavir has been ingested.

There are no restrictions on food, beverages, or activities while taking entecavir otherwise directed by your physician. 

Store:

Store entecavir in the original carton at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep entecavir out of the reach of children and away from pets.

Approx. Rs 8,500 / BottleGet Latest Price

Velakastmanufactured by Natco and marketedAprazer is the combination Velpatasvir 100mg & Sofosbuvir 400mg and is used to treatment of chronic (long-lasting) hepatitis C, a viral infection of the liver(HCV). Velakast is also used with another antiviral medication (ribavirin). Velakast work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.

Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer which will be cure by Velakast

Velakast -Sofosbuvir 400 mg & velpatasvir 100 mg is used alone or with ribavirin to treat chronic hepatitis C. Velakast -Sofosbuviris in a class of antiviral medications called nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Velakast -Velpatasviris in a class of antiviral medications called HCV NS5A replication complex inhibitors.

The Velakast combination of sofosbuvir and Velpatasvir works by stopping the virus that causes hepatitis C from spreading inside the body

Additional Information:

Approx. Rs 5,500 / BottleGet Latest Price

Ledviclear (Ledipasvir & Sofosbuvir)

• Brand name: Ledviclear
• Active Ingeridents(Generic Name) : Ledipasvir & Sofosbuvir
• Company Name: Abbott
• Package: 28 tablets/bottle
• Strength : Ledipasvir 90mg & Sofosbuvir 400mg

Indication:

Treating chronic hepatitis C virus (HCV) infection in certain patients.

Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.

Mechanism of action:

Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.

Dosage and Administration:

Ledipasvir-sofosbuvir (90 mg/400 mg) is a fixed-dose combination tablet . The recommended dosage is one tablet once daily, with or without food.

Side effects:

The following are the Common side effects

· fatigue

• nausea
• headache
• diarrhea

· insomnia

Precaution:

· Tell your doctor or dentist that you take ledipasvir and sofosbuvir before you receive any medical or dental care, emergency care, or surgery.

· Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HCV to others.

Store: ledipasvir & Sofosbuvir room temperature away from moisture and heat

Approx. Rs 8,500 / BottleGet Latest Price

Hepcinat LP (Ledipasvir & Sofosbuvir)

Brand name: Hepcinat LP

Active Ingeridents(Generic Name) : Ledipasvir & Sofosbuvir

Company Name: Natco

Package: 28 tablets/bottle

Strength : Ledipasvir 90mg & Sofosbuvir 400mg

Indication:

Treating chronic hepatitis C virus (HCV) infection in certain patients.

Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Mechanism of action:

Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.

Dosage and Administration:

Ledipasvir-sofosbuvir (90 mg/400 mg) is a fixed-dose combination tablet . The recommended dosage is one tablet once daily, with or without food.

Side effects:

The following are the Common side effects

· fatigue

nausea
headache
diarrhea

· insomnia

Precaution:

· Tell your doctor or dentist that you take ledipasvir and sofosbuvir before you receive any medical or dental care, emergency care, or surgery.

· Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HCV to others.

Store: ledipasvir & Sofosbuvir room temperature away from moisture and heat

Approx. Rs 1,600 / BottleGet Latest Price

Dactovin (Daclatasvir )

• Brand name: Qurdac
• Active Ingeridents(Generic Name) : Daclatasvir
• Company Name: Strides
• Package: 28 Tablets/Bottle
• Strength : 60 mg

Indication:

Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Mechanism of action:

The dimeric symmetry of these compounds suggests that they act on a dimer of NS5A, which is also consistent with the presence of dimers in crystals of NS5A domain 1 from genotype 1b. Genotype 1a HCV is less potently affected by these compounds and resistance mutations have a greater effect than in the 1b genotypes. We have obtained crystals of domain 1 of the important 1a NS5A homologue and intriguingly, our X-ray crystal structure reveals two new dimeric forms of this domain. Furthermore, the high solvent content (75%) makes it ideal for ligand-soaking. Daclatasvir (DCV) shows twofold symmetry suggesting NS5A dimers may be of physiological importance and serve as potential binding sites for DCV. These dimers also allow for new conformations of a NS5A expansive network which could explain its operation on the membranous web. Additionally, sulfates bound in the crystal structure may provide evidence for the previously proposed RNA binding groove, or explain regulation of NS5A domain 2 and 3 function and phosphorylation.

Dosage and Administration:

Take daclatasvir exactly as your healthcare provider tells you to.

· Do not change your dose unless your healthcare provider tells you to.

· Do not stop taking daclatasvir without first talking with your healthcare provider.

· Take daclatasvir 1 time each day with or without food.

The recommended usage of daclatasvir to treat chronic hepatitis C virus is 60 mg taken orally once daily with or without food in combination with sofosbuvir. The recommended treatment duration is 12 weeks.

Side effects:

Tiredness, headache, nausea, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Precaution: Before taking daclatasvir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:. Daclatasvir room temperature away from moisture and heat.

Additional Information:

Approx. Rs 1,600 / BottleGet Latest Price

Indication:

Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Dosage and Administration:

Take daclatasvir exactly as your healthcare provider tells you to.

· Do not change your dose unless your healthcare provider tells you to.

· Do not stop taking daclatasvir without first talking with your healthcare provider.

· Take daclatasvir 1 time each day with or without food.

The recommended usage of daclatasvir to treat chronic hepatitis C virus is 60 mg taken orally once daily with or without food in combination with sofosbuvir. The recommended treatment duration is 12 weeks.

Additional Information:

Approx. Rs 2,700 / BottleGet Latest Price

Indication:

Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir  and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Dosage and Administration:

Take daclatasvir exactly as your healthcare provider tells you to.

· Do not change your dose unless your healthcare provider tells you to.

· Do not stop taking daclatasvir without first talking with your healthcare provider.

· Take daclatasvir 1 time each day with or without food.

The recommended usage of daclatasvir to treat chronic hepatitis C virus is 60 mg taken orally once daily with or without food in combination with sofosbuvir. The recommended treatment duration is 12 weeks.

Approx. Rs 1,350 / PieceGet Latest Price

Entavir (Entecavir)

Brand name: Entavir

Active Ingeridents(Generic Name) : Entecavir

Company Name: Cipla

Package: 10 Tablets

Strength : 1mg

Indication: Entecavir is used to treat long-term hepatitis B infection. Hepatitis B is an infection of the liver caused by the hepatitis B virus. Long-term infection can cause liver damage, rarely liver cancer, and liver failure. Entecavir helps to decrease the amount of hepatitisB virus in your body. It is unknown if this medication lowers your chance of gettingliver cancer or liver damage. Entecavir is an antiviral that belongs to a class of drugs known as hepatitis B virus nucleoside reverse transcriptase inhibitors.

Mechanism of action:

Entecavir is mainly used to treat chronic hepatitis B infection in adults and children 2 years and older with active viral replication and evidence of active disease.It is also used to prevent HBV reinfection after liver transplant and to treat HIV patients infected with HBV. Entecavir is weakly active against HIV, however it is not recommended for use in HIV-HBV co-infected patients without a fully suppressive anti-HIV regimen as it may select for resistance to lamivudine and emtricitabine in HIV.

Dosage and Administration:

· Take entecavir on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal.

· Entecavir works best if it is taken at the same time each day.

· Continue to take entecavir even if you feel well. Do not miss any doses.

· If you miss a dose of entecavir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

Dizziness; headache; nausea; tiredness.

Precaution:

An overdose entecavir Unlikely to threaten life, call an emergency room or a poison control center for advice if you suspect that a very large dose of entecavir has been ingested.

There are no restrictions on food, beverages, or activities while taking entecavir otherwise directed by your physician.

Store:

Store entecavir in the original carton at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep entecavir out of the reach of children and away from pets.

Approx. Rs 2,500 / PieceGet Latest Price

Ribahep ( Ribavirin)

Brand name: Ribahep

Active Ingeridents(Generic Name) : Ribavirin

Company Name: Zydus heptiza

Package: 140 Capsules/Bottle

Strength : 200mg

Indication:

Ribahep ( Ribavirin) is used in combination with other antiviral medications to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. Ribahep ( Ribavirin) works by reducing the amount of hepatitis C virus in your body, which may help your liver recover.

Mechanism of action:

Ribahep ( Ribavirin) is readily phosphorylated intracellularly by adenosine kinase to Ribahep ( Ribavirin) mono-, di-, and triphosphate metabolites. Ribahep ( Ribavirin) triphosphate (RTP) is a potent competitive inhibitor of inosine monophosphate (IMP) dehydrogenase, viral RNA polymerase and messenger RNA (mRNA) guanylyltransferase (viral) and can be incorporated into RNA in RNA viral species.. Guanylyltranserase inhibition stops the capping of mRNA. These diverse effects result in a marked reduction of intracellular guanosine triphosphate (GTP) pools and inhibition of viral RNA and protein synthesis. Ribahep ( Ribavirin) is also incorporated into the viral genome causing lethal mutagenesis and a subsequent decrease in specific viral infectivity.

Dosage and Administration:

Use Ribahep ( Ribavirin) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Ribahep ( Ribavirin) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Ribahep ( Ribavirin) refilled.

· Take Ribahep ( Ribavirin) by mouth with food.

· Drinking extra fluids while you are taking Ribahep ( Ribavirin) is recommended. Check with your doctor for instructions.

Ask your health care provider any questions you may have about how to use Ribahep ( Ribavirin).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; dry mouth; dry skin; hair loss; joint pain; loss of appetite; mild headache, nausea, or vomiting; mild stomach pain; tiredness; trouble sleeping; upset stomach; weakness or fatigue.

Precaution:

Before taking Ribahep ( Ribavirin), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Ribahep ( Ribavirin) between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ribahep ( Ribavirin) out of the reach of children and away from pets.