Nephrology

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Introduction:

Graftide S 360mg Tablet contains mycophenolic acid as the active constituent. This medicine is indicated for patients who have undergone transplants that include liver, kidney, and heart. This medication is given to avoid organ rejections. Rejections occur when our immune system identifies the new organ as a foreign body attacks it. This medication is given in combination with other medications such as corticosteroids and ciclosporin which also possess immunosuppressive action. It is advised not to switch over to sound alike medication i.e Mycophenolate mofetil, without any medical advice. 

If you are a woman of childbearing It is required to show negative pregnancy reports before commencing the first dose of Graftide S 360mg Tablet. This medicine is not recommended for pregnant women as it causes birth defects or miscarriage. For men, it is advised to not donate semen until 90 days after treatment completion. Inform your physician if you ever had gastric-related problems such as ulcers or gastric bleeding. Inform your doctor if you are taking any antibiotics or antacids before starting this medicine as it might affect the effectiveness of the drug.

It is advised to limit your exposure to sunlight while you are on treatment with this medicine because it is found that Graftide S 360mg Tablet makes your skin more vulnerable to sunlight and increases the risk of skin cancer. Report to your doctor if you develop any signs of infection. It is advised to avoid donating blood for 6 weeks after the completion of your treatment. However, your doctor may perform a check on your antibodies and blood cell count before starting the treatment. This medication is unsafe to use for children below the age of 5 years. 

Uses of Graftide S 360mg Tablet:

Graftide S 360mg Tablet are been approved for treating the following conditions:

• Prophylaxis for kidney transplant patients to prevent organ rejection.
• For children above 5 years of age who have had their kidney transplants.

How Graftide S 360mg Tablet works:

Graftide S 360mg Tablet is an enteric-coated tablet that will pass via the stomach and get dissolved in the intestine. This medicine belongs to the class of immunosuppressive agents that reversibly inhibits the enzyme inosine monophosphate dehydrogenase which plays a significant role in purine synthesis. Therefore it affects the immune cells and impairs them to produce antibodies in response to new organ transplantation. This medicine has been developed for gastric tolerability.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

How to use Graftide  S 360mg Tablet:

• Consume Graftide S 360mg Tablet as exactly prescribed by your doctor.
• Swallow this tablet as a whole with water.
• Do Not crush or break the tablets.
• This Tablet is to be consumed on empty stomach either 1 hour before or after food.

Safety advice:

Pregnancy:

It is unsafe to consume Graftide S 360mg Tablet during pregnancy as it can cause birth defects. If you planning for pregnancy, it is better to discuss with your doctor regarding the harmful effect of the medicine on the baby and follow the contraception advice strictly.

Breastfeeding:

It is important that you inform your doctor if you are breastfeeding or planning to breastfeed because Graftide S 360mg Tablet tends to pass into breastmilk.

Liver: 

Inform your doctor if you have had a history of liver diseases or infections such as hepatitis because Graftide S 360mg Tablet is to be used with caution in these patients.

Additional Information:

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Uses

Gemcitabine is used to treat certain types of cancer (including breast, lung, ovarian, pancreatic). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

How to use Gemcitabine HCL Vial

This medication is given by injection into a vein by a healthcare professional. It is given over 30 minutes as directed by your doctor. The dosage is based on your medical condition, body size, and response to treatment.

Additional Information:

Approx. Rs 1,220 / VialGet Latest Price

Gemcite 200mg Injection is a chemotherapy medication containing the active ingredient gemcitabine. It is used to treat bladder cancer, breast cancer, ovarian cancer, pancreatic cancer, and non-small cell lung cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. Talk to your doctor if you have heart disease, liver disorders, kidney disorders, recently had radiotherapy, or vaccinated before taking this medicine. 

Gemcite 200mg Injection is not recommended for adolescents and children under the age of 18. Your doctor will assess your blood cell counts, kidney and liver function before each time you are given this medicine. Use effective birth control during the treatment and for at least six months after the last dose. 

Tell your physician if you are on a salt-controlled diet as this medicine contains sodium. Report your doctor immediately if you experience shortness of breath, wheezing, changes in colour or volume of urine, bleeding, or upper abdominal pain while taking Gemcite 200mg Injection.

Uses of Gemcite 200mg Injection:

Gemcite 200mg Injection is used to treat

• Bladder cancer, in combination with cisplatin
• Ovarian cancer, in combination with carboplatin
• Breast cancer, in combination with paclitaxel
• Pancreatic cancer
• Non-small cell lung cancer (NSCLC), alone or in combination with cisplatin

How Gemcite 200mg Injection works:

Gemcite 200mg Injection inhibits the enzyme thymidylate synthetase, resulting in inhibition of DNA synthesis in the cancer cells. This prevents the growth of cancer cells.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Gemcite 200mg Injection out of sight and reach of children.
• Store at controlled room temperature 20°C to 25°C.

 How to use Gemcite 200mg Injection:

It will be given to you by a doctor or nurse. 

Safety advice:

Pregnancy:

Gemcite 200mg Injection can cause harm to your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medication. It will be given to you if clearly needed.

Breastfeeding:

You must not breastfeed while being treated with this medication. Inform your doctor if you are breastfeeding before taking Gemcite 200mg Injection.

Liver:

You need to tell your doctor if you have any liver disorders before taking Gemcite 200mg Injection. Your doctor may decide to adjust the dose or delay treating you depending on your liver function.

Kidney:

You need to tell your doctor if you have any kidney disorders before taking Gemcite 200mg Injection. Your doctor may decide to adjust the dose or delay treating you depending on your kidney function.

Driving: 

Gemcite 200mg Injection could affect your ability to drive. Avoid driving if you feel sleepy.

Others:

Inform your doctor if:

• You have heart disease, recently had radiotherapy, or vaccinated before taking this medicine.
• You are on a salt-controlled diet.
• You experience shortness of breath, wheezing, changes in colour or volume of urine, bleeding, or abdominal pain while taking this medication.

• Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

   

  Serious:

  • Pulmonary toxicity (shortness of breath, wheezing, cough)
  • Hemolytic-uremic syndrome

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